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Letter to the Editor

Do Antihypertensives Make Tranylcypromine Safer? Three Case Reports

Bonnie P. Taylor, PhD; Frederic M. Quitkin, MD; Patrick J. McGrath, MD; and Jonathan W. Stewart, MD

Published: May 15, 2005

Article Abstract

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Sir: Monoamine oxidase inhibitors (MAOIs) have neverbeen widely prescribed because of the risk of hypertensionwhen combined with tyramine-containing foods or sympathomimeticamine drugs.1 Hypertensive reactions have also beenreported, albeit less frequently, in patients who adhere to MAOIdietary restrictions. While some of these so-called spontaneoushypertensive reactions have been reported to occur shortly afterMAOI ingestion, others appear unrelated to the time of drugintake.

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Volume: 66

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