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Letter to the Editor

Applying Parsimony to “An African Patient With Ziprasidone Intolerance.”

Jeffrey L. Anders, MD

Published: November 15, 2005

Article Abstract

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Sir: Awareness of and sensitivity to ethno-pharmacologic issues are vital when treating a person of a particular cultural/racial background, but it seems equally important to apply the principle of parsimony to cases like the one described in a recent (June 2005) letter by Hein and colleagues ("An African Patient with Ziprasidone Intolerance").1 The authors suggest that their patient, who was of Nubian, Arabic, and Irish background, was particularly sensitive to a typical 40 mg b.i.d. dose of ziprasidone because of his "African ethnicity." They bolstered their claim by citing this case as the second report of a person of African background who experienced severe side effects from a "commonly recommended dose of ziprasidone."

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Volume: 66

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