Reliability and Validity of the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)

David V. Sheehan, MD, MBA; Kathy H. Sheehan, PhD; R. Douglas Shytle, PhD; Juris Janavs, MD; Yvonne Bannon, RN, MSHS; Jamison E. Rogers, MD; Karen M. Milo, PhD; Saundra L. Stock, MD; and Berney Wilkinson, PhD

Published: March 15, 2010

Article Abstract

Objective: To investigate the concurrent validity and reliability of the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID), a short structured diagnostic interview for DSM-IV and ICD-10 psychiatric disorders in children and adolescents.

Method: Participants were 226 children and adolescents (190 outpatients and 36 controls) aged 6 to 17 years. To assess the concurrent validity of the MINI-KID, participants were administered the MINI-KID and the Schedule for Affective Disorders and Schizophrenia for School Aged Children-Present and Lifetime Version (K-SADS-PL) by blinded interviewers in a counterbalanced order on the same day. Participants also completed a self-rated measure of disability. In addition, interrater (n = 57) and test-retest (n = 83) reliability data (retest interval, 1-5 days) were collected, and agreement between the parent version of the MINI-KID and the standard MINI-KID (n = 140) was assessed. Data were collected between March 2004 and January 2008.

Results: Substantial to excellent MINI-KID to K-SADS-PL concordance was found for syndromal diagnoses of any mood disorder, any anxiety disorder, any substance use disorder, any ADHD or behavioral disorder, and any eating disorder (area under curve [AUC] = 0.81-0.96, κ = 0.56-0.87). Results were more variable for psychotic disorder (AUC = 0.94, κ = 0.41). Sensitivity was substantial (0.61-1.00) for 15/20 individual DSM-IV disorders. Specificity was excellent (0.81-1.00) for 18 disorders and substantial (> 0.73) for the remaining 2. The MINI-KID identified a median of 3 disorders per subject compared to 2 on the K-SADS-PL and took two-thirds less time to administer (34 vs 103 minutes). Interrater and test-retest kappas were substantial to almost perfect (0.64-1.00) for all individual MINI-KID disorders except dysthymia. Concordance of the parent version (MINI-KID-P) with the standard MINI-KID was good.

Conclusions: The MINI-KID generates reliable and valid psychiatric diagnoses for children and adolescents and does so in a third of the time as the K-SADS-PL.

Trial Registration: clinicaltrials.gov Identifier: NCT00579267

J Clin Psychiatry 2010;71(3):313-326

Submitted: April 19, 2009; accepted July 23, 2009.

Corresponding author: David V. Sheehan, MD, MBA, Depression & Anxiety Disorders Research Institute, University of South Florida College of Medicine, 3515 East Fletcher Ave, Tampa, FL 33613-4706 (dsheehan@health.usf.edu).

Volume: 71

Quick Links: Assessment Methods , Diagnostic Tools

Continue Reading…

Subscribe to read the entire article

$40.00

Buy this Article as a PDF

References

Sign-up to stay
up-to-date today!

SUBSCRIBE

Already registered? Sign In

Original Research

Frontothalamic Circuit Abnormalities in Patients With Bipolar Depression and Suicide Attempts

To identify potential markers for suicide risk, this fMRI study looked at neural activity in bipolar depression...

Read More...