This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Focus on Alzheimer's Disease and Related Disorders

In This Issue: Genetics, Cholesterol, and the Risk of Alzheimer’s Disease

Eric M. Reiman, MD

Published: July 15, 2005

Article Abstract

Because this piece has no abstract, we have provided for your benefit the first 3 sentences of the full text.

In recent years, researchers have made significant progress in understanding factors that may modify the risk of Alzheimer’s disease (AD). Known genetic risk factors include mutations of the presenilin 1 (PS1), presenilin 2 (PS2), and amyloid precursor protein (APP) genes and the apolipoprotein E (APOE) ε4 allele. The relatively uncommon PS1, PS2, and APP mutations cause a form of the disorder typically characterized by dementia onset before the age of 60 and autosomal dominant inheritance.’ ‹

Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Related Articles

Volume: 66

Quick Links: Assessment Methods , Genetics

Sign-up to stay
up-to-date today!


Already registered? Sign In

Clinical and Practical Psychopharmacology

Skeletal and Dental Fractures Associated With Electroconvulsive Therapy

Recent data suggest the risk of skeletal or dental fracture with ECT may be as low as...