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Challenges and Algorithm-Guided Treatment in Major Depressive Disorder

Richard C. Shelton, MD, and Madhukar H. Trivedi, MD

Published: April 15, 2011

Article Abstract

Major depressive disorder is complicated and difficult to treat, primarily because of its chronic and recurrent nature and the poor efficacy of most pharmacologic treatment options. Until more effective treatments become available, clinicians must focus on optimizing patient outcomes through patient care. Implementing measurement-based care and using treatment algorithms can reduce symptoms of depression and help patients achieve and maintain remission.

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