Management of Patients With Treatment-Resistant Depression
Treatment-resistant depression can be attributed to multiple causes, including nonadherence to medication and medical and psychiatric comorbidities. Selecting the appropriate strategy for a patient with treatment-resistant depression, whether it be a single antidepressant, a combination of medications, or a nonpharmacologic method, depends on a correct determination of the cause of the patient’s resistance to treatment.
J Clin Psychiatry 2008;69(3):e08
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