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Academic Highlights

Novel Antidepressant Strategies to Optimize Outcome

 

Published: September 30, 2000

Article Abstract
A resurgence of interest in the potent neurotransmitter norepinephrine (NE) and its role in depression has led investigators to realize that norepinephrinereuptake inhibitors (NRIs) may have a greater impact on drive, motivation, energy, and social functioning than selective serotonin reuptake inhibitors (SSRIs). This realization is the result of research on approaches to optimize the outcomes of patients with depression, whereby NE and serotonin have been compared with respect to their effects on antidepressant mechanisms of action and efficacy.

Volume: 61

Quick Links: Depression (MDD)

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Letter to the Editor

Stigma Kills Psychiatric Patients and Is Now Killing Clinical Research Too

Robert M. Post, MD, argues that NIMH should abandon the RDoC framework and restore funding for clinical...

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