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Letters to the Editor

SSRI-TCA Combination in the Treatment of Resistant Depression

Takeshi Terao and Naomi Ikemura

Published: July 31, 2000

Article Abstract

Letter to the Editor

Sir: We read with interest the article by Levitt et al. that showed the effect of combining the selective serotonin reuptake inhibitor (SSRI) fluoxetine and a tricyclic antidepressant (TCA) in resistant depression. Seth et al. also showed that 8 cases of resistant recurrent depression were successfully treated with a combination of nortriptyline and an SSRI, although Levitt et al. did not cite their article.


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