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Early-Stage Alzheimer Primer: Pathophysiology, Diagnosis, and Assessment

Liana Apostolova, MD, MSca

Published: May 4, 2021

Alzheimer disease (AD) is the most common cause of dementia; in the United States alone, approximately 5.8 million people are living with the disease. This slide presentation offers education about AD pathogenesis, trajectory, and diagnostic criteria from the Diagnostic and Statistical Manual of Disorders, Fifth Edition, and from the National Institute on Aging–Alzheimer’s Association. To diagnose mild cognitive impairment and early-stage AD, clinicians should employ a stepwise process that includes the following: cognitive screening, laboratory assessments, structural imaging of the brain, full neuropsychologic assessment (if warranted), and biomarker confirmation.

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Find more articles on this and other psychiatry and CNS topics:
The Journal of Clinical Psychiatry
The Primary Care Companion for CNS Disorders

To read more on the subject, go to the related Academic Highlights

To cite: Apostolova L. Early-stage Alzheimer primer: pathophysiology, diagnosis, and assessment. J Clin Psychiatry. 2021;82(3):BG20044WC1C.
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aIndiana University School of Medicine, Indianapolis.

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