This CME activity is expired. For more CME activities, visit CMEInstitute.com.
Find more articles on this and other psychiatry and CNS topics:
The Journal of Clinical Psychiatry
The Primary Care Companion for CNS Disorders
Article Abstract
Bipolar disorder is a highly episodic illness, and many patients require long-term or lifelong treatment to maintain a stable mood. Because depression is the dominant pole of both bipolar I and bipolar II disorder, maintenance therapy must prevent depressive recurrence. Although numerous treatment options exist for bipolar disorder, few have data supporting both short-term and long-term efficacy for bipolar depression. When choosing among treatments, clinicians must consider the existing evidence for the long-term effectiveness of various pharmacologic and psychosocial interventions for controlling all types of mood events.
Vol 87 • 2026 • Number 1
Read the Current Issue
Original Research
Innovation in Psychiatric Drug Development: A Quantitative Analysis of FDA-Approved Psychiatric Drugs, 2012–2024
Meta-Analysis
Effectiveness of Peer-Administered Interventions for Perinatal Depression or Anxiety
Original Research
Effect of Adjuvant Metformin on Adherence to and Persistence of Treatment With SGAs in Nondiabetic Patients
Editorial
Thank You to the JCP Community
Editorial
Psychotherapy: Integral to Clinical Psychiatry
Original Research