This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

CME Activity

Cognitive-Behavioral Management of Drug-Resistant Major Depressive Disorder

Giovanni A. Fava, Gianni Savron, Silvana Grandi, and Chiara Rafanelli

Published: June 15, 1997

This CME activity is expired. For more CME activities, visit CMEInstitute.com.
Find more articles on this and other psychiatry and CNS topics:
The Journal of Clinical Psychiatry
The Primary Care Companion for CNS Disorders


Article Abstract

Background: The application of cognitive-behavioral treatment to drug-resistant major depression has received little research attention.

Method: Nineteen patients who failed to respond to at least two trials of antidepressant drugs of adequate dosages and duration were treated by cognitive-behavioral methods in an open trial.

Results: Three patients dropped out of treatment. The remaining 16 patients displayed a significant (p

Conclusion: These preliminary results suggest that a trial of cognitive-behavioral therapy by an experienced therapist should be performed before labeling an episode of major depression as “refractory” or “treatment resistant.” These latter terms should apply only when a psychotherapeutic effort has been made. Until then, it seems more appropriate to define depression as “drug refractory” or “drug treatment resistant.”

Volume: 58

Quick Links: Cognition , Neurologic and Neurocognitive

Continue Reading…

Subscribe to read the entire article

$40.00

Buy this Article as a PDF

References

Sign-up to stay
up-to-date today!

SUBSCRIBE

Already registered? Sign In

Clinical and Practical Psychopharmacology

Skeletal and Dental Fractures Associated With Electroconvulsive Therapy

Recent data suggest the risk of skeletal or dental fracture with ECT may be as low as...

Read More...