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Letters to the Editor

Risperidone-Induced Ejaculatory and Urinary Dysfunction

Subramoniam Madhusoodanan, MD and Ronald Brenner, MD

Published: November 15, 1996

Article Abstract

Letter to the Editor

Sir: Risperidone is a benzisoxazole derivative antipsychoticagent with serotonin 5-HT2 and dopamine D2 antagonistic properties.During premarketing evaluation of this compound, diminishedsexual desire, erectile dysfunction, and orgasmic dysfunctionwere noted in at least 5% of patients.1 In addition,product information lists dysuria and other urinary difficultiesamong risperidone’s adverse events.

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