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CME Academic Highlights

Early Recognition and Treatment of Tardive Dyskinesia in Patients With Mood Disorders and Schizophrenia


Tardive dyskinesia (TD), a potentially irreversible condition that causes involuntary movements associated with dopamine receptor blocking agents, can substantially impair patients’ functioning and diminish their quality of life. While TD was expected to vanish due to more widespread use of second-generation antipsychotics than use of first-generation antipsychotics, in reality, more patients than ever are at risk for developing this condition. Early detection and accurate diagnosis of TD is critical to increasing chances that TD movements will be transient and reversible. Clinicians must be proactive in regularly screening patients for TD, educating the patient and family about risk factors, addressing psychosocial concerns related to the condition, and selecting one of the novel, FDA-approved medications—valbenazine or deutetrabenazine—to treat TD symptoms. Providing a clinical TD diagnosis as early as possible is crucial to implementing treatment strategies that may successfully reduce patients’ TD symptoms.

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J Clin Psychiatry 2020;81(1):NU18041AH5C

To cite: McEvoy JP, Kremens DE. Early recognition and treatment of tardive dyskinesia in patients with mood disorders and schizophrenia. J Clin Psychiatry. 2020;81(1):NU18041AH5C
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From the Department of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University (Dr McEvoy); and the Department of Neurology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania (Dr Kremens).

Volume: 81

Quick Links: Neurologic and Neurocognitive , Neurology