This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.


Measuring Treatment Efficacy in Insomnia

Thomas Roth, PhD

Published: May 1, 2004

Article Abstract

The measurement of insomnia treatment efficacy has evolved over time. Historically, patient reportmeasures were used to assess sleep the previous night, and, although important, these measureswere not objectively validated. While the advent of polysomnography complemented patient reportsof nocturnal sleep, few studies have evaluated daytime functioning and impact of impaired sleep oncomorbid medical and psychiatric illnesses as measures of the efficacy of hypnotics. In the future,therapeutic endpoints will focus on important factors associated with insomnia, such as enhancedalertness, improved outcomes associated with augmentation therapy for depression, reduction in painseverity, and decreased sleep disturbances associated with hot flashes.

Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Related Articles

Volume: 65

Quick Links: Neurologic and Neurocognitive , Neurology

Sign-up to stay
up-to-date today!


Already registered? Sign In

Case Report

Safety and Tolerability of Concomitant Intranasal Esketamine Treatment With Irreversible, Nonselective MAOIs: A Case Series

Three cases suggest that concomitant use of intranasal esketamine with an irreversible, nonselective MAOI is safe in...