This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Letters To the Editor

Divalproex Versus Olanzapine in Mania

Article Abstract

Because this piece does nothave an abstract, we have provided for your benefit the first 3 sentencesof the full text.

Sir: The article by Zajecka et al.1on the efficacy and safetyof divalproex sodium versus olanzapine in the treatment ofbipolar disorder is interesting, but unfortunately it does notseem to truly support the authors’ conclusions.The first problem is sample size. According to previous experience with divalproex2and olanzapine,3this study was notclearly powered to show superiority of either drug over theother and it is unclear whether this trial was designed to proveeither superiority or noninferiority.’ ‹’ ‹


Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Volume: 64

Quick Links: Neurologic and Neurocognitive , Seizure