This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Letters to the Editor

Carbamazepine Augmentation of Clomipramine in the Treatment of Refractory Obsessive-Compulsive Disorder

Article Abstract

Letter to the Editor

Sir: The serotonin reuptake inhibitors (SRIs) are now considered first-choice agents for the pharmacologic treatment of obsessive-compulsive disorder (OCD). However, many patients with OCD are nonresponders or partial responders to these agents. Although the augmentation therapy of these agents with neuroleptics, lithium, benzodiazepines, or buspirone is recommended to treat refractory OCD, the efficacy of the augmentation strategy is still limited. The case presented here illustrates effective augmentation of clomipramine, an SRI, with carbamazepine in the treatment of a patient with OCD refractory to the previously recommended treatment strategies.


Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Related Articles

Volume: 61

Quick Links: Obsessive-Compulsive and Related Disorders