This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Articles

Update on Pharmacologic Management of OCD: Agents and Augmentation

Article Abstract

A preponderance of patients with obsessive-compulsive disorder (OCD) experience little or no improvementin their symptoms when treated with serotonin reuptake inhibitors (SRIs). It is hypothesizedthat SRI-refractory patients may have altered serotonin neurotransmission different frompatients responsive to SRIs, or that they may have abnormalities in their dopamine function. Whendrugs affecting serotonin function (e.g., tryptophan, fenfluramine, lithium, buspirone) are added toSRI therapy in SRI-refractory patients, results are mixed and not consistently encouraging. However,when drugs affecting dopamine function (e.g., pimozide, haloperidol, risperidone) are added to SRItherapy in SRI-refractory OCD patients, individuals with either a personal history or family history oftics experience a reduction in their symptoms.


Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Volume: 58

Quick Links: Obsessive-Compulsive and Related Disorders

Sign-up to stay
up-to-date today!

SUBSCRIBE

Already registered? Sign In

Original Research

Recovering From Intimate Partner Violence Through Strengths and Empowerment: Findings From a Randomized Clinical Trial

This RCT focused on a psychosocial counseling intervention for women experiencing intimate partner violence (IPV). Outcomes such...

Read More...