This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Letters to the Editor

Valproate Monotherapy in an SRI-Intolerant OCD Patient

Article Abstract

Sir: Many patients with obsessive-compulsive disorder (OCD) considered to be treatment refractory have prematurely discontinued serotonin reuptake inhibitors (SRIs) due to side effects (such as irritability and anxiety) and are not truly treatment refractory. Some OCD patients intolerant of SRIs had decreased adverse effects after pretreatment with valproic acid. We therefore pretreated an OCD patient intolerant of standard doses of fluoxetine, sertraline, and clomipramine with valproic acid.


Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Related Articles

Volume: 59

Quick Links: Obsessive-Compulsive and Related Disorders