This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Educational Activity

Practical Strategies for Diagnosing and Treating Depression in Women: Menopausal Transition

Claudio N. Soares, M.D., Ph.D., F.R.C.P.C.

Published: October 31, 2008

This CME activity is expired. For more CME activities, visit
Find more articles on this and other psychiatry and CNS topics:
The Journal of Clinical Psychiatry
The Primary Care Companion for CNS Disorders

Article Abstract

Major depressive disorder (MDD) is a common and debilitating condition that affects twice as many women as men. Accumulated evidence suggests that hormone fluctuations may play an important role in such increased risk for depression among females. For example, women during the menopausal transition appear to have a heightened risk for developing MDD compared with premenopausal or postmenopausal women. Overlapping depressive and menopause-related symptoms (e.g., vasomotor complaints, sleep disturbances) can complicate diagnosis and treatment, but it is vital that clinicians work to adequately tailor their treatment strategies to manage both the mood and somatic symptoms. Possible treatment options to be considered include the adequate use of hormone replacement therapy, antidepressants, psychotherapy, and other psychotropic agents.

Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Related Articles

Volume: 69

Quick Links: