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Letters To the Editor

Can Bilateral Prefrontal Repetitive Transcranial Magnetic Stimulation (rTMS) Induce Mania?A Case Report

Armand Hausmann, MD; Karin Kramer-Reinstadler, MD; Theresia Lechner-Schoner, MD; Michaela Walpoth, MD; Claudia I. Rupp, PhD; Hartmann Hinterhuber, MD

Published: November 1, 2004

Article Abstract

Because this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.

Sir: Bilateral repetitive transcranial magnetic stimulation(rTMS) using high-frequency (hf-rTMS) and low-frequency (lf-rTMS) stimulation over the left and right dorsolateral prefrontal cortex (DLPFC), respectively, was theorized to enhance antidepressant outcome.1 Although efficacy is discussed controversially, 2,3 this stimulation paradigm at least did not induce nocuous cognitive impairments.2,4 Cases of affective side effects have been reported with use of hf-rTMS over the left DLPFC5,6 and with use of lf-rTMS over the right DLPFC.7


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Volume: 65

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