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Method. The sample for our study investigating the association between olanzapine and hyperglycemia consisted of 109 patients treated with olanzapine in Yamanashi Prefectural Kita Hospital (Nirasaki, Japan) who had not been diagnosed with diabetes mellitus before starting olanzapine therapy (Table 1). To clarify the incidence of hyperglycemia related to olanzapine therapy, we performed a fasting glucose test (after obtaining informed consent). We also retrospectively checked glucose values during olanzapine treatment prior to this fasting glucose test. Hyperglycemia was defined as a fasting glucose level ≥ 126 mg/dL or a random glucose level ≥ 200 mg/dL. If hyperglycemia appeared more than 2 times, diabetes mellitus was diagnosed.


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Volume: 65

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