psychiatrist

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Psychobiology and Psychosocial Functioning of Schizoaffective Disorder

Christoph U. Correll, MD

Published: February 15, 2011

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Find more articles on this and other psychiatry and CNS topics:
The Journal of Clinical Psychiatry
The Primary Care Companion for CNS Disorders


Article Abstract

Data from neurobiologic and psychosocial outcomes research suggest that, phenomenologically, clinically, and neurobiologically, patients with schizoaffective disorder occupy an intermediate position between more severely disturbed schizophrenia patients and similarly or less severely impaired affective disorder patients. Some biologic-genetic abnormalities are shared between these disorders, while other abnormalities are specific to particular symptoms. Premorbid functioning, especially in academic areas, is better in patients with schizoaffective disorder than in those with schizophrenia, but negative symptoms and cognitive deficits are influential and should be addressed to improve psychosocial outcomes.


 

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