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Educational Activity

Role of Antidepressants in Bipolar Depression

Eduard Vieta, MD, PhD

Published: September 15, 2010

This CME activity is expired. For more CME activities, visit
Find more articles on this and other psychiatry and CNS topics:
The Journal of Clinical Psychiatry
The Primary Care Companion for CNS Disorders

Article Abstract

A gap exists between the standard of care for bipolar depression and actual clinical practice. Although practice guidelines advise against treating bipolar depression with antidepressant monotherapy, this is the most frequently prescribed initial treatment. To provide quality care and improve patient outcomes, clinicians must be aware of the benefits and dangers of antidepressant use in bipolar disorder. Further, they must be informed about alternative, more efficacious treatment options for patients with depressive symptoms.


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