This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Free Online Activities

Neurobiology and the Natural History of Schizophrenia

Jeffrey A. Lieberman

Published: October 1, 2006

Article Abstract

Schizophrenia follows afairly consistent natural history and longitudinal course of illness, and itcan be described in the context of four specific clinical stages—the premorbid,prodromal, deterioration, and chronic/residual stages. Many patients treated intheir first episode of schizophrenia respond well to treatment and achieve somesymptom remission and level of recovery, but recurrent episodes, often broughton by treatment nonadherence or insufficient treatment, lead to moresubstantial and lasting neurologic deterioration. This presentation describesthe clinical stages of schizophrenia and discusses the possibility forprevention of clinical deterioration with early detection and treatment of theillness and sustained maintenance treatment after episodic remission.

This CME activity is expired. For more CME activities, visit cme.psychiatrist.com.
Find more articles on this and other psychiatry and CNS topics:
The Journal of Clinical Psychiatry
The Primary Care Companion for CNS Disorders

Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Related Articles

Volume: 67

Quick Links: Schizophrenia and Schizoaffective Disorders

References

Sign-up to stay
up-to-date today!

SUBSCRIBE

Already registered? Sign In

Clinical and Practical Psychopharmacology

Antipsychotic Augmentation With N-Acetylcysteine for Patients With Schizophrenia

Dr Andrade discusses whether or not recent findings support the use of NAC as antipsychotic augmentation in...

Read More...