This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Letters To the Editor

Addition of Lamotrigine to Clozapine in Inpatients With Chronic Psychosis

Adolph H. Heck, MD; Izaäk W. de Groot, MSc; and Peter N. van Harten, PhD

Published: October 14, 2005

Article Abstract

Because this piece has no abstract, we have provided for your benefit the first 3 sentences of the full text.

Sir: Two studies have reported a substantial reductionof symptoms when the anticonvulsant drug lamotrigine wasadded to clozapine in patients with treatment-resistant schizophrenia.1,2 We report on 6 inpatients with persistent and severepsychotic symptoms who were treated for 24 weeks with a combinationof lamotrigine and clozapine.

Method. The study, which was conducted between December2000 and August 2002, was approved by an independentmedical ethics committee, and all patients gave informed consent.

Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Related Articles

Volume: 66

Quick Links: Psychotic Disorders , Schizophrenia and Schizoaffective Disorders


Sign-up to stay
up-to-date today!


Already registered? Sign In

Case Report

Safety and Tolerability of Concomitant Intranasal Esketamine Treatment With Irreversible, Nonselective MAOIs: A Case Series

Three cases suggest that concomitant use of intranasal esketamine with an irreversible, nonselective MAOI is safe in...