This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Letters to the Editor

Polypharmacy of 2 Atypical Antipsychotics

Article Abstract

Letter to the Editor

Sir: I am writing to respond to the BRAINSTORMS article by Dr. Stephen Stahl in the July 1999 issue of the Journal. I agree that polypharmacy should be avoided. I was a resident in the early 1970s, when even having a person on treatment with an antidepressant and diazepam was considered a serious therapeutic misadventure. In his article, Dr. Stahl stated that no justification exists for using 2 expensive atypical antipsychotics and that this mixture usually results from being trapped in a cross-titration between 2 atypical agents without an adequate trial of monotherapy. I describe a case of a patient who did receive adequate trials of clozapine and olanzapine but nevertheless did best on a mixture of the 2 drugs.


Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Related Articles

Volume: 61

Quick Links: Psychotic Disorders , Schizophrenia and Schizoaffective Disorders