This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Letters to the Editor

AMPA Blockade May Be the Mechanism Underlying the Efficacy of Topiramate in PTSD

Article Abstract

Sir: We read with great interest the report of Berlant and van Kammen on topiramate in posttraumatic stress disorder (PTSD). They report particularly on suppression of nightmares and flashbacks and propose the suppression of kindling mechanisms as underlying topiramate’s efficacy for these symptoms. We would propose a further possible mechanism, which has not been considered by the authors.


Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Related Articles

Volume: 64

Quick Links: PTSD , Trauma