This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.


Vasomotor Symptoms and Depression in Women, Part 2. Treatments That Cause Remission and Prevent Relapses of Major Depressive Episodes Overlap With Treatments for Vasomotor Symptoms

Stephen M. Stahl, MD, PhD

Published: March 16, 2009

Article Abstract

Vasomotor symptoms may be
linked to changing levels of
estrogen, which can affect levels of
neurotransmitters and neural proteins
that modulate the risk of depression in
some women, thus serving as harbingers
of oncoming depression or signs
of incomplete recovery from a major
depressive episode (MDE). The
question arises whether clinicians who
normally diagnose and treat depression
should also diagnose and treat vasomotor
symptoms, and if so, how.

Fluctuating estrogen levels can theoretically
create monoaminergic dysfunction
in the brain; when this dysregulation
occurs in the hypothalamic thermoregulatory centers, vasomotor
symptoms may occur (Figure 1).

Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Related Articles

Volume: 70

Quick Links: