Research Methodology
Page 4
Recently published articles about Research Methods and Statistics
Clinical and Practical Psychopharmacology
Methylphenidate and the Risk of New-Onset Seizures
July 21, 2020
Concerns have been expressed that stimulant drugs may increase seizure risk, but some studies also suggest otherwise. This column considers the findings in the context of the study methodologies...
Clinical and Practical Psychopharmacology
Genes as Confounds in Studies of Neurodevelopmental Outcomes After Antidepressant Prescription During Pregnancy
May 26, 2020
Observational studies have found associations between antidepressant drug prescription during pregnancy and autism and ADHD. But is the link actually related to genetic predisposition rather than to the antidepressant?...
Clinical and Practical Psychopharmacology
Prenatal Maternal Anemia as a Potential Confound in Studies on Neurodevelopmental and Other Outcomes
March 31, 2020
An association between antidepressants during pregnancy and neurodevelopmental disorders has been found in many observational studies. But is anemia part of the culprit? Dr Andrade takes a closer look...
Clinical and Practical Psychopharmacology
Antidepressants and Risk of Hip Fracture in the Elderly
July 30, 2019
Dr Andrade considers the findings of observational studies indicating a higher risk of hip fracture in older people who take antidepressants—and whether confounding by indication can fully explain the...
Clinical and Practical Psychopharmacology
Offspring Outcomes in Antidepressant-Treated Pregnancies
March 29, 2017
Both untreated depression and prenatal exposure to antidepressants have been associated with adverse outcomes. In this month's column, Dr Andrade describes possible study design' ’related contributors that are important...
Clinical and Practical Psychopharmacology
Propensity Score Matching in Nonrandomized Studies
February 22, 2017
Propensity score matching, or the probability that a subject will receive a particular treatment, is one way to address baseline differences between treatment groups in observational studies. In this...
