Alleviation of Hot Flashes With Increase in Venlafaxine Dose

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Sir: Venlafaxine, a newer bicyclic antidepressant, acts as a serotonin-norepinephrine reuptake inhibitor (SNRI). Besides improving depressive symptoms, venlafaxine has also been demonstrated to alleviate vasomotor symptoms.1 It is being increasingly used as a nonhormonal drug to treat hot flashes, mostly in those women with concerns about or contraindications to estrogen-containing preparations.2​​

Prim Care Companion J Clin Psychiatry 2007;9(1):70-71