Olanzapine for the Treatment of Bipolar Disorder

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Sir: In a recent issue of the Companion, Masand and colleagues1 report a retrospective analysis of 36 outpatients with bipolar or schizoaffective disorder in which risperidone and olanzapine were comparable in efficacy and safety, but treatment costs were lower for risperidone-treated patients. Although the acquisition costs of risperidone are lower than those of olanzapine, when other factors are taken into account, the costs of the 2 agents do not differ appreciably. As the authors point out in their article, atypical antipsychotics are becoming commonly prescribed agents in primary care settings.​

Prim Care Companion J Clin Psychiatry 2002;4(3):113-114