Uses of Newer Anticonvulsants: An Update

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Sir: Since the publication of a recent review of the psychiatric uses of newer anticonvulsants in the Companion,1 2 new anticonvulsants have come to market. The first is levetiracetam, which is U.S. Food and Drug Administration–approved as an adjunctive agent in treating partial-onset seizures in adults with epilepsy.2 Its precise mechanism of action is not known, but does not appear to be due to any interaction with known mechanisms involved in inhibitory or excitatory neurotransmission.3

Prim Care Companion J Clin Psychiatry 2002;4(5):200