Original Research

Original Research

First-Episode Nonaffective Psychoses

June 22, 2016

Proper diagnosis can present a moving target for patients presenting with first-episode nonaffective psychosis. Find out how missing the mark can affect your patients' long-term outcome.

Mauricio Tohen , Stephen M. Strakowski , Ross J. Baldessarini , et al

Original Research

Late-Onset Psychiatric Disorder in Injury Survivors

June 22, 2016

PTSD, depression, and substance abuse can develop up to 6 years after a traumatic injury, often going undiagnosed after standard medical follow ups end. See how social support, level...

Richard A. Bryant , Mark Creamer , Derrick Silove , et al

Original Research

Long-Term Mental Health and Military Service

June 22, 2016

Which factor has the biggest impact on veterans' long-term mental health outcomes? Length of service? Combat? Rank? The authors of this new Online First study explore this question, with...

Beverly P. Bergman , Daniel F. Mackay , Daniel J. Smith , et al

Original Research

Personality and Long-Term Outcome of Depression

June 22, 2016

Can personality affect depression outcomes? Yes, according to this new study. The authors discovered that cluster C personality disorders, neuroticism, and extraversion influence the outcome of first-episode depression in...

Lars V. Kessing , Jens D. Bukh , Per K. Andersen

Original Research

SSRIs and Glaucoma

June 22, 2016

Is SSRI use associated with glaucoma? The authors of this Online First study investigated the relationship between recent SSRI use and the risk of acute angle-closure glaucoma in the...

Cheng-Li Lin , Chia-Hung Kao , Hsin-Yi Chen , et al

Original Research

Still Depressed?

June 22, 2016

Could a handshake indicate a patient's depression is in remission? In this study, handgrip force was measured in remitted, depressed, and healthy subjects to identify factors that influenced the...

Philippe Fossati , Thomas Mauras , Marc Masson , et al

Original Research

Adherence to Antidepressants Is Associated With Lower Mortality: A 4-Year Population-Based Cohort Study

May 25, 2016

Can adherence to antidepressants lead to a longer lifespan? In this new Online First study, consider how clinicians can decrease a patient's risk of mortality.

Amir Krivoy , Ran D. Balicer , Becca Feldman , et al

Original Research

Clozapine and Risperidone in Moderately Refractory Schizophrenia: A 6-Month Randomized Double-Blind Comparison

May 25, 2016

Stephen R. Marder , Daniel Umbricht , John M. Kane , et al

Original Research

Comparative Risk of Antipsychotic-Related Seizure

May 25, 2016

Seizure risk can influence whether you choose an FGA or SGA for your patients with schizophrenia or mood disorders. This analytical review of seizure events in almost 300,000 new...

Chi-Shin Wu , Sheng-Chang Wang , I-Jin Yeh , et al

Original Research

Correlation of Clinical Response With Homocysteine Reduction During Therapy With Reduced B Vitamins in Patients With MDD Who Are Positive for MTHFR C677T or A1298C Polymorphism: A Randomized, Double-Blind, Placebo-Controlled Study

May 25, 2016

Are reduced B vitamins effective as antidepressant monotherapy? Read this free article to find out. The authors evaluated the efficacy and safety of reduced B vitamins in adults with...

Arnold W. Mech , Andrew Farah

Original Research

Early Interventions to Prevent PTSD

May 25, 2016

What is the best method to pull acute PTSD patients from the depths of their anguish? This trial tested cognitive and prolonged-exposure therapy and SSRI treatment over 12 weeks....

Arieh Y. Shalev , Yael Ankri , Moran Gilad , et al

Original Research

Efficacy Outcomes From 3 Clinical Trials of Edivoxetine as Adjunctive Treatment for Patients With Major Depressive Disorder Who Are Partial Responders to Selective Serotonin Reuptake Inhibitor Treatment

May 25, 2016

Mary Anne Dellva , Margaret B. Ferguson , Susan G. Ball , et al

Original Research

Long-Term Efficacy, Safety, and Tolerability of l-Methylfolate Calcium 15 mg as Adjunctive Therapy With Selective Serotonin Reuptake Inhibitors: A 12-Month, Open-Label Study Following a Placebo-Controlled #05#

May 25, 2016

Maurizio Fava , George I. Papakostas , Richard C. Shelton , et al

Original Research

Suicide Risk After Traumatic Injury

May 25, 2016

Traumatic injury increases the risk for a psychiatric disorder, and it could lead to suicidal risk. This prospective cohort study covers factors affecting risk and who the patient will...

Richard A. Bryant , Meaghan L. O' Donnell , Mark Creamer , et al

Original Research

Trauma and Age at Exposure

May 25, 2016

What's the impact of childhood trauma on a patient's psychopathological profile? To answer this question, Dr Alameda and colleagues looked at whether early psychosis patients with trauma before age...

Philippe Conus , Luis Alameda , Philippe Golay , et al

Original Research

Bilirubin Concentration Correlates With Positive Symptoms in Patients With Schizophrenia

April 27, 2016

W. Wolfgang Fleischhacker , Georg Kemmler , Alex Hofer , et al

Original Research

Change in Employment Status in Bipolar Disorder: A Longitudinal Study Using National Claims Data

April 27, 2016

Hui-Chih Chang , Kuan-Chih Huang , Wei-Che Chiu , et al

Original Research

Clinical Outcome After Antipsychotic Treatment Discontinuation in Functionally Recovered First-Episode Nonaffective Psychosis Individuals: A 3-Year Naturalistic Follow-Up Study

April 27, 2016

Obdulia Martínez-García , Benedicto Crespo-Facorro , Jacqueline Mayoral-van Son , et al

Original Research

High False-Positive Rate of a Putative Biomarker Test to Aid in the Diagnosis of Schizophrenia

April 27, 2016

Cheryl A. Wehler , Sheldon H. Preskorn

Original Research

New-Onset Depression Risk with Hyperlipidemia

April 27, 2016

"Read a study whether preexisting hyperlipidemia increases the risk of another depressive episode & the role of statin medications in new-onset depression."

Hsiao-Yue Wee , Chung-Han Ho , Fu-Wen Liang , et al

Original Research

The Long-Term Psychiatric Sequelae of Severe Injury: A 6-Year Follow-Up Study

April 27, 2016

Richard A. Bryant , Meaghan L. O' Donnell , Derrick Silove , et al

Original Research

Prediction of Nonremission to Antidepressant Therapy Using Diffusion Tensor Imaging

April 27, 2016

A. John Rush , Leanne M. Williams , Stuart M. Grieve , et al

Original Research

Probability and Correlates of Dependence Among Regular Users of Alcohol, Nicotine, Cannabis, and Cocaine: Concurrent and Prospective Analyses of the National Epidemiologic Survey on Alcohol and Related Conditions

April 27, 2016

Michael J. Zvolensky , Jesse R. Cougle , Jahn K. Hakes , et al

Original Research

Sleep Disturbance in Chronic Military-Related PTSD: Clinical Impact and Response to Adjunctive Risperidone in the Veterans Affairs Cooperative Study #504

April 27, 2016

Robert A. Rosenheck , Robert H. Pietrzak , Andrew D. Krystal , et al

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