Carol Lim, MD, MPH

The authors describe a patient with schizophrenia who effectively reversed substantial clozapine-induced weight gain using tirzepatide, followed by weight regain after insurance-related discontinuation.

A patient with treatment-resistant schizophrenia whose presumed oculogyric crisis was later identified as seizure-like activity, worsened with clozapine and resolved with antiepileptic treatment.

In this young man, continuous video-EEG monitoring revealed undiagnosed seizures that, once treated, helped resolve his catatonia and reduce symptoms of schizophrenia.