David Grimes, MD

Department of Medicine (Neurology), University of Ottawa Brain and Mind Institute and Ottawa Hospital Research Institute, Ottawa, Ontario, Canada

JCP
Original Research

March 16, 2026

Neuropsychiatric symptoms in Alzheimer’s disease separate into hyperactivity, psychosis, neurovegetative, and affective clusters, supporting a cluster-based paradigm linking behavioral symptoms with brain structure and functional decline.
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Consensus Report on XT Use in Practice

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Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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