Jeremy Franklin, PhD

If an antidepressant doesn' t seem to be working, what is your next move? This meta-analysis compares efficacy and tolerability of increasing antidepressant dose versus continuing the initial dose....

After you start patients on antidepressant therapy, how long should it take for them to respond? This meta-analysis looks at existing data to estimate the probability of additional response...

Is it the drug or is it the natural course of depression that explains why patients remit at 6 months? Read this systematic review and meta-analysis to discover how...