Lauren Astorino, MSN
Yale Depression Research Program, Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut; Yale Center for Clinical Investigation, Yale School of Medicine, New Haven, Connecticut
Original Research
CBT following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention: The CBT-ENDURE Randomized Trial
May 4, 2026
In patients with major depression and suicidal ideation, adding a 16-week CBT course to esketamine led to greater improvements in suicidal ideation and depression severity than esketamine alone.
