Oleksandr Sverdlov, PhD

  • 2Articles
  • 29.3KReads1
  • 2021–2025Active
  • 21Collaborators
  • 25Citations2

About

Oleksandr Sverdlov, PhD, affiliated with Novartis Pharmaceuticals Corporation in East Hanover, New Jersey, has published research focused on treatments for depression, including major depressive disorder and bipolar depression. His work includes clinical trials investigating the efficacy of Onfasprodil, a novel NR2B negative allosteric modulator, and the antidepressant citalopram in acute and preventive settings. Sverdlov's publications span from 2021 to 2025 and appear in Psychiatrist.com journals.

Publications

JCP
Onfasprodil (MIJ821) in Patients with Treatment-Resistant Depression: A Phase 2, Randomized, Placebo-Controlled, Proof-of-Concept Study
Original Research

Onfasprodil (MIJ821) in Patients with Treatment-Resistant Depression: A Phase 2, Randomized, Placebo-Controlled, Proof-of-Concept Study

August 6, 2025

Onfasprodil appeared to be effective and well-tolerated across all dosing regimens in patients with TRD and demonstrated rapid onset of action (24 hours) with evidence of antidepressant effects to...
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JCP
Original Research

Efficacy of Citalopram Treatment in Bipolar Depression

January 12, 2021

Antidepressants are widely used to treat bipolar illness, though their effectiveness in this disorder has not been established. This randomized, double-blind, placebo-controlled trial assessed the efficacy and safety of...
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