Peter Karalis, MD

Behavioral Health Department, Community Health Network, Indianapolis, Indiana

PCC
Mania and Cerebral Amyloid Angiopathy
Case Report

March 19, 2026

This report details a case in which a patient presented with mania in the setting of cerebral amyloid angiopathy and hypertension that did not abate until treatment with antihypertensives.
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PCC
Case Report

December 23, 2021

Systemic inflammation can alter serum clozapine levels, requiring careful consideration for COVID-19–positive patients in whom a strong inflammatory response may occur. Read on to find out more.
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Consensus Report on XT Use in Practice

Read the full report
Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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