Stephen Stahl, MD, PhD

Department of Psychiatry and Neuroscience, University of California, Riverside, Riverside, California

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About

Stephen Stahl, MD, PhD, is affiliated with the Department of Psychiatry and Neuroscience at the University of California, Riverside. His publications in 2025 focus on major depressive disorder, covering topics such as the history and development of MAOI antidepressants, advances in precision psychiatry for depression treatment, and clinical trials of lumateperone as adjunctive therapy. He has frequently collaborated with co-authors including Roger S. McIntyre, Allan Young, Changzheng Chen, Chittaranjan Andrade, and Claudia Albeldas.

Publications

JCP
MAOI Antidepressants: A History Being Rewritten
Commentary

MAOI Antidepressants: A History Being Rewritten

November 26, 2025

Members of the International MAOI Expert Group discuss historical use of MAOIs, consider their efficacy and safety, and underscore the importance of reassessing their place in treatment algorithms.
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PCC
Precision Psychiatry for Depression Treatment
Narrative Review

Precision Psychiatry for Depression Treatment

September 9, 2025

Novel precision medicine tools in depression aim to identify the optimal treatment for each patient and have the potential to significantly improve depression management by guiding treatment selection for...
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JCP
Lumateperone as Adjunctive Therapy in MDD: A Randomized, Double-Blind, Phase 3 Trial
Original Research

Lumateperone as Adjunctive Therapy in MDD: A Randomized, Double-Blind, Phase 3 Trial

August 25, 2025

In patients with MDD with inadequate antidepressant response, adjunctive lumateperone 42 mg significantly improved depression symptoms and severity versus adjunctive placebo, and it was generally well tolerated.
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