This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.


Antidepressants in Panic Disorder

James W. Jefferson, M.D.

Published: April 1, 1997

Article Abstract

Antidepressants have been used to treat patients with panic disorder almost since these drugs werefirst introduced. Tricyclic antidepressants, monoamine oxidase inhibitors (MAOIs), serotonin selectivereuptake inhibitors (SSRIs), and other antidepressants have all been studied, with varying results,in patients with panic disorder. The MAOIs are believed by some clinicians to be the most potent antipanicagents, but their considerable side effects limit their use. The tricyclic antidepressants imipramineand clomipramine are well established in treating panic disorder, although today many clinicianschoose an SSRI as their first-line agent. Data supporting this clinical preference for SSRIs are justnow becoming available.

Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Volume: 58

Quick Links: Depression (MDD)

Sign-up to stay
up-to-date today!


Already registered? Sign In

Original Research

Sublingual Dexmedetomidine for the Treatment of Acute Agitation in Adults With Schizophrenia or Schizoaffective Disorder: A Randomized Placebo-Controlled Trial

This RCT determined whether a single dose of sublingual dexmedetomidine reduced acute agitation associated with schizophrenia or...