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Letter to the Editor

Efficacy of Quetiapine in Generalized Social Anxiety Disorder: Results From an Open-Label Study

Sara I. J. Schutters, MD; Harold J. G. M. van Megen, MD; and Herman G. M. Westenberg, PhD

Published: April 15, 2005

Article Abstract

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Sir: The generalized form of social anxiety disorder is ahighly prevalent psychiatric condition that causes persistentfunctional impairment.1 Although selective serotonin reuptakeinhibitors (SSRIs) have become the first-line treatment for socialanxiety disorder,2 these drugs do not always give adequatesymptom relief, and side effects like initial increase of anxiety,gastrointestinal complaints, and sexual dysfunction can complicatetheir long-term use.Animal models have shown that atypical antipsychoticsalso possess anxiolytic properties.3-5‘ ‹

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