This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

CME Activity

DSM-IV Intermittent Explosive Disorder: A Report of 27 Cases

Susan L. McElroy, Cesar A. Soutullo, DeAnna A. Beckman, Purcell Taylor, Jr., and Paul E. Keck, Jr.

Published: April 15, 1998

This CME activity is expired. For more CME activities, visit CMEInstitute.com.
Find more articles on this and other psychiatry and CNS topics:
The Journal of Clinical Psychiatry
The Primary Care Companion for CNS Disorders


Article Abstract

Background: The authors’ objective was toprovide data regarding the demographic, phenomenological, courseof illness, associated psychiatric and medical comorbidity,family history, and psychiatric treatment responsecharacteristics of rigorously diagnosed subjects who met DSM-IVcriteria for intermittent explosive disorder.

Method: Twenty-seven subjects meeting DSM-IVcriteria for a current or past history of intermittent explosivedisorder were given structured diagnostic interviews. Thesubjects’ medical histories, family histories of psychiatricdisorders, and responses to psychiatric treatments were alsoassessed.

Results: Most subjects described theirintermittent explosive disorder symptoms as very distressingand/or highly problematic. All 27 subjects described aggressiveimpulses prior to their aggressive acts. Of 24 subjects who weresystematically queried, 21 (88%) experienced tension with theimpulses; 18 (75%), relief with the aggressive acts; and 11(48%), pleasure with the acts. Most subjects stated that theiraggressive impulses and acts were also associated with affectivesymptoms, particularly changes in mood and energy level.Twenty-five (93%) subjects had lifetime DSM-IV diagnoses of mooddisorders; 13 (48%), substance use disorders; 13 (48%), anxietydisorders; 6 (22%), eating disorders; and 12 (44%), animpulse-control disorder other than intermittent explosivedisorder. Subjects also displayed high rates of comorbid migraineheadaches. First-degree relatives displayed high rates of mood,substance use, and impulse-control disorders. Twelve (60%) of 20subjects receiving monotherapy with an antidepressant or a moodstabilizer reported moderate or marked reduction of theiraggressive impulses and/or episodes.

Conclusion: Intermittent explosive disorderappears to be a bona fide impulse-control disorder that may berelated to mood disorder and may represent another form ofaffective spectrum disorder.

Volume: 59

Quick Links: Conduct Disorders , Impulse-Control Disorders

Continue Reading…

Subscribe to read the entire article

$40.00

Buy this Article as a PDF

References

Sign-up to stay
up-to-date today!

SUBSCRIBE

Already registered? Sign In

Case Report

Safety and Tolerability of Concomitant Intranasal Esketamine Treatment With Irreversible, Nonselective MAOIs: A Case Series

Three cases suggest that concomitant use of intranasal esketamine with an irreversible, nonselective MAOI is safe in...

Read More...