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Long-Term Treatment of Recurrent and Chronic Depression

Martin B. Keller, MD

Published: January 11, 2001

Article Abstract

Depression is associated with high rates of impairment and comorbidity with other disorders andhas a devastating effect on those who suffer from it. Treatment options are available and can greatlyimprove functioning; however, undertreatment still persists. Undertreatment may result from incorrector incomplete diagnoses or inadequate treatment duration. In addition, when treating depression,clinicians must identify underlying conditions, life-span issues, and proper treatment duration tomaximize outcome. This article provides an overview of the underlying implications of depression,reviews issues in treating chronic depression that are still unresolved, and recommends standards formaintenance therapy.

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