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Insights

Emerging Treatments in Schizophrenia Video

Christoph U. Correll, Anissa Abi-Dargham, and Oliver Howes

Published: February 17, 2022

Experts discuss the brain circuits involved in schizophrenia, the current medications, and new agents in phase 3 trials that do not directly block postsynaptic D2 receptors. Phase 2 data on one of these agents, the TAAR1 agonist ulotaront, are summarized.

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Quick Links: Psychopharmacology , Schizophrenia and Schizoaffective Disorders

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Original Research

Generalizability of the Results of Efficacy Trials in First-Episode Schizophrenia: Comparing Outcome and Study Discontinuation of Groups of Participants in the Optimization of Treatment and Management of Schizophrenia in Europe (OPTiMiSE) Trial

First-episode schizophrenia patients with suicidal ideation and substance use disorder are often excluded from clinical trials. Omitting...

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