May 11, 2021
In this webcast about early-stage Alzheimer disease, Drs Burke and Apostolova highlight important conversations to have with patients and their care partners on topics such as diet, exercise, driving, and plans for the later stage of illness.
A Change in Blood Carbamazepine Levels Associated With Cannabis Use: Implications for Clinical Practice
This report describes carbamazepine level fluctuations that occurred concurrent with stopping and restarting of cannabis use in a patient with bipolar disorder.
Case reports suggest a link between obsessive-compulsive disorder (OCD) and dementia, but this association has received little research. The current study investigated dementia risk among OCD patients using a national health insurance research database.
Therapeutic Response Is Associated With Antipsychotic-Induced Weight Gain in Drug-Naive First-Episode Patients With Schizophrenia: An 8-Week Prospective Study
How does weight gain during antipsychotic treatment relate to therapeutic response? This 8-week study investigates the question.
Great strides in research on Alzheimer disease diagnostic biomarkers and treatment targets have taken place over the past 2 decades. Listen as Dr Goldfarb highlights exciting developments.
May 4, 2021
What are the steps for diagnosing Alzheimer disease? Are you familiar with diagnostic criteria and assessment tools? In this webcast, walk through the process with an expert.
What are some of the challenges you face in overcoming adherence issues and providing patient-centered care for people living with schizophrenia? Drs Harvey and Kane offer evidence and clinical experience on these topics in this journal CME activity.
Trends in Medication Prescribing in Patients With PTSD From 2009 to 2018: A National Veterans Administration Study
Although psychotherapy is available via the Veterans Health Administration, most veterans diagnosed with posttraumatic stress disorder (PTSD) receive pharmacotherapy. This study evaluated longitudinal prescription practice trends for veterans with PTSD.
This comprehensive meta-analysis informs clinicians and patients about the potential effectiveness of omega-3 fatty acids as add-on therapy for borderline personality disorder.
April 27, 2021
Izuhara and colleagues reply to a letter commenting on their recent article.
Transdiagnostic Psychiatric Symptoms, Burnout, and Functioning in Frontline Health Care Workers Responding to the COVID-19 Pandemic: A Symptomics Analysis
The pandemic has clearly placed a tremendous strain on health care workers, but how has it affected their ability to function in their daily lives and the likelihood of burnout? This large survey from a New York hospital provides some answers.
Antipsychotics can be used in the short term to manage dementia-related psychosis, but serious adverse effects can outweigh benefits. Novel antipsychotics or other agents may offer superior efficacy and safety. Explore the evidence in this CME activity.
This letter comments on a recent JCP article by Izuhara et al.
April 20, 2021
Posttraumatic Distress Symptoms and Their Response to Treatment in Adults With Prolonged Grief Disorder
Posttraumatic stress disorder and prolonged grief disorder (PGD) both arise following major life stressors. This study examined the presence and response to treatment of posttraumatic stress symptoms in bereaved adults with a primary diagnosis of PGD.
April 13, 2021
Cross-Sectional Associations Among Symptoms of Pain, Irritability, and Depression and How These Symptoms Relate to Social Functioning and Quality of Life: Findings From the EMBARC and STRIDE Studies and the VitalSign6 Project
Is pain associated with irritability and depression? This study aimed to evaluate relationships between these symptom categories and determine how they may relate to functional impairments.
Antipsychotic Use and Bloodstream Infections Among Adult Patients With Chronic Obstructive Pulmonary Disease: A Cohort Study
Antipsychotics may have immunomodulatory effects that could increase the risk of disseminated infections. This study sought to estimate the effect of antipsychotics on incident bloodstream infections in adults with chronic obstructive pulmonary disease.
April 6, 2021
Persons With Debt Burden Are More Likely to Report Suicide Attempt Than Those Without: A National Study of US Adults
Suicide rates are increasing, but understanding of its predictors is incomplete, especially regarding self-perceived financial well-being. This study assessed the association between debt burden and self-reported suicide attempt among US adults.
The COVID-19 pandemic has affected the daily life of millions worldwide, with still unclear effects on mental health. This study examined patterns in pediatric psychiatric visits to hospital emergency departments in Italy during the pandemic lockdown.
March 30, 2021
Active Placebo, the Parachute Meta-Analysis, the Nobel Prize, and the Efficacy of Electroconvulsive Therapy
Electroconvulsive therapy has a negative connotation in many circles, but is it getting a bad rap? Dr Andrade offers thoughtful counterpoints to the criticism.
In this letter, Dr Hernandez and colleagues reply to a letter from Brigido et al that comments on their recent article on the impact of comorbid posttraumatic stress disorder on outcomes of treatment with repetitive transcranial magnetic stimulation in depressed veterans.
Screening Tests Are Not Diagnostic: A Commentary on a Study of Electroconvulsive Therapy for Depressed Patients With and Without Borderline Personality Disorder
This commentary discusses a recent article on the use of electroconvulsive therapy for depressed patients with and without borderline personality disorder.
Posttraumatic Stress Disorder Symptom Severity Does Not Predict Depression Improvement, but May Impact Clinical Response and Remission
This letter to the editor builds on the findings of a recent article by Hernandez and colleagues on the impact of comorbid posttraumatic stress disorder on outcomes of treatment with repetitive transcranial magnetic stimulation in depressed veterans.
Both frailty and late-life depression are associated with higher mortality rates. This study explored the association of physical frailty with mortality in depressed older patients.
March 23, 2021
Can a patient-centered approach to treatment be adopted for patients with schizophrenia? Can these patients take part in shared decision-making? Follow along as Dr Harvey shares his expertise.
Patients may be more willing to accept some adverse effects than others. Dr Kane offers advice on addressing side effects that prevent patients from maintaining their medication adherence.
Could prazosin help patients with alcohol use disorder who experience intense withdrawal symptoms? Dr Andrade considers the evidence and the findings of a recent large RCT.
Insomnia, Suicidal Ideation, and Suicide Attempts in the Clinical Antipsychotic Trials of Intervention Effectiveness
Insomnia is common in schizophrenia, but how does it affect suicidality and symptoms in these patients? This analysis of CATIE data provides answers.
Are women who have postpartum psychiatric episodes more likely to get a divorce than women who do not experience such episodes? Read this report of a population-based cohort study to learn more.
High Prevalence and Incidence of Obsessive-Compulsive Disorder Among Women Across Pregnancy and the Postpartum
When screening for perinatal OCD, do you ask infant-specific questions? If not, patients may not make the connection to their symptoms. Learn more in this journal CME article.
March 16, 2021
Insomnia is often comorbid with psychiatric, medical, and neurologic disorders. Follow along as Dr Rosenberg discusses the bidirectional relationship between insomnia disorder and frequently co-occurring conditions.
The link between suicidality and interpersonal difficulties extends the traditional approach of comprehending suicide as mainly related to depression. This study of adult outpatients investigated the link between separation anxiety disorder and suicidality.
To diagnose insomnia disorder, how do you conduct an effective interview with patients? What assessment tools do you use? Review the evaluation process with an expert.
Telehealth Treatment of Patients in an Intensive Acute Care Psychiatric Setting During the COVID-19 Pandemic: Comparative Safety and Effectiveness to In-Person Treatment
Because of COVID-19, much behavioral health care is now delivered virtually. Is this as effective as in-person treatment? Read the article to learn more.
The Prevalence and National Burden of Treatment-Resistant Depression and Major Depressive Disorder in the United States
How prevalent is treatment-resistant depression (TRD), and what proportion of the burden of medication-treated major depressive disorder is accounted for by TRD? This study explores those questions using the most commonly accepted definition of TRD.
March 9, 2021