Successful Treatment of Binge Eating Disorder With Combination Phentermine/Topiramate Extended Release

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To the Editors: Phentermine/topiramate extended release is a novel medication approved as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in obese adults. To our knowledge, phentermine/topiramate extended release has not yet been evaluated in binge eating disorder, which often co-occurs with obesity. We therefore present 2 patients with binge eating disorder and obesity who experienced cessation of binge-eating behaviors and clinically significant weight loss with phentermine/topiramate extended release.