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Letter to the Editor

Monocytosis Subsequent to Ziprasidone Treatment: A Possible Side Effect

Jan Thöne, MD, and Elke Kessler, MD

Published: December 14, 2007

Article Abstract

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Sir: Ziprasidone is an atypical antipsychotic agent that is available as oral and short-acting intramuscular formulations and is approved by the U.S. Food and Drug Administration for management of schizophrenia and bipolar disorder. Ziprasidone acts as a serotonin and dopaminereceptor antagonist, with greater affinity for the 5-HT2Areceptor than the dopamine D2 receptor.1 Moreover, it possesses agonist activity at the serotonin 5-HT1A receptor.1

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Volume: 9

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