Advancing primary care with essential peer-reviewed research and insights into CNS disorders
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More Articles from The Primary Care Companion for DNS Disorders
Brief Report
Beneficial Effects of the Sigma-1 Agonist Fluvoxamine for Tardive Dyskinesia in Patients With Postpsychotic Depressive Disorder of Schizophrenia: Report of 5 Cases
November 8, 2012
Tardive dyskinesia (TD) is characterized by involuntary, repetitive, purposeless movements that can affect different parts of the body. Tardive dyskinesia is a well-known side effect of conventional antipsychotics and…
Article
Depression, Quality of Life, Work Productivity, Resource Use, and Costs Among Women Experiencing Menopause and Hot Flashes: A Cross-Sectional Study
November 1, 2012
In this article, review results from a study that examined the effect of depression on health-related quality of life, work productivity, resource use, and costs among women experiencing menopausal…
Rounds from Banner Alzheimer’s Institute
A Wolf in Sheep’s Clothing: When Behaviors Imply Dementia
October 25, 2012
Engage in this interactive CME case study. In this issue of the Companion, we highlight the case of a 61-year-old woman with short-term memory deficits, word-finding difficulty, increasing repetition…
Article
Aripiprazole Partial Agonism at 5-HT2C: A Comparison of Weight Gain Associated With Aripiprazole Adjunctive to Antidepressants With High Versus Low Serotonergic Activities
October 18, 2012
Aripiprazole is a partial agonist at several receptor sites, one of which is 5-HT2C, which has been associated with increased food intake. The authors of this study theorize that…
Article
The Effect of Personality Disorder Symptoms on Response to Treatment With Methylphenidate Transdermal System in Adults With Attention-Deficit/Hyperactivity Disorder
October 11, 2012
This trial was designed to prospectively explore the relationship among personality disorder (PD) symptoms, attention-deficit/hyperactivity disorder (ADHD), and treatment response in a randomized, double-blind, crossover clinical trial of methylphenidate…
Article
The Effectiveness of Antidepressant Monotherapy in a Naturalistic Outpatient Setting
October 4, 2012
The objective of this study was to assess a representative sample of clinically depressed outpatients during acute treatment with antidepressant medication monotherapy to determine clinical outcomes and evaluate relationships…