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Letter to the Editor

Possible New Causes For False-Positive Diagnosis of Pheochromocytoma: Lamotrigine, Aripiprazole, or the Combination

Vijay Shivaswamy, MD; Whitney S. Goldner, MD; and Joseph Erwin, MD

Published: April 16, 2007

Article Abstract

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Sir: Pheochromocytomas are rare neuroendocrine tumorsdiagnosed by elevated plasma and/or urine catecholamines ortheir metabolites.1,2 Medications reported to cause false-positiveserum or urine studies include acetaminophen, phenoxybenzamine,amitriptyline, labetolol, haloperidol, levodopa, tamsulosin,venlafaxine, hydrochlorothiazide, and buspirone.2,3 Wereport a case in which lamotrigine, aripiprazole, or both causedsymptoms and biochemical evidence suggesting pheochromocytomathat resolved when the drugs were discontinued.

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Volume: 9

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